PEMODELAN MOLEKUL SENYAWA TURUNAN KOJIC ACID SERTA INTERAKSINYA DENGAN ENZIM TIROSINASE
نویسندگان
چکیده
منابع مشابه
Cinnamic Acid Derivate From the Bark of Lerchea bracteata Val
Penyelidikan kandungan kimia dari batang tumbuhan Lerchea brateata Val telah dilakukan dan berhasil mendapatkan senyawa asam 3,4-dihidroksisinamatmetil ester yang diisolasi dari fraksi etil asetat menggunakan metoda kromatografi. Senyawa ini dimurnikan melalui proses rekristalisasi dan berbentuk kristal kekuningan dan meleleh pada 162-163 o C. Struktur dielusidasi melalui interprestasi spektrum...
متن کاملKojic Acid Derivatives
Melanin is one of the most important pigments which exist ubiquitously from microorganisms to plants and animals. It is secreted by melanocyte cells and determines the color of skin and hair in mammalians. It protects the skin from photocarcinogenesis by absorbing UV sunlight and removing reactive oxygen species (ROS) (Gupta, 2006; Kim, 2005; Sapkota, 2011). It is formed by enzymatically cataly...
متن کاملThe Biosynthesis of Kojic Acid
Barker, S. B., Kiely, C. E., Dirks, H. B., Klitgaard, H. M., Wang, S. C. & Wawzonek, S. (1950). J. Phlarmacol. 99, 202. Barnes, J. H., Elks, J., Stephens, F. F. & Waller, G. J. (1953). J. chem. Soc. p. 764. Cortell, R. E. (1949). J. clin. Endocrin. 9, 955. Datta, R. L. & Prosad, N. (1917). J. Amer. chem. Soc. 39, 443. Frieden, E. & Winzler, R. J. (1949). J. biol. Chem. 179, 423. Kalb, L., Schwe...
متن کاملControl of Phytophthora palmivora on Orchids with Some New Systemic and Standard Fungicides
Tiga fungisida serap yang baru iaitu Aliette (efosite-Al), Ridomil (metalaxyl) serta Ridomil MZ (metalaxyl dengan mancozeb) dan dua fungisida biasa Terrazole (etridiazole) serta Difolatan (captafol) telah diuji kesan profilaktik dan terapeutik ke atas Phytophthora palmivora pada orkid. Pucuk-pucuk punca haibrid Aranda Christine dapat dikawal dengan berkesan daripada jangkitan Phytophthora apabi...
متن کاملKojic acid-derived tyrosinase inhibitors: synthesis and bioactivity
Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables. Kojic acid is a naturally-occurring tyrosinase inhibitor which has been clinically used to treat the hyperpigmentation of skin. However, kojic a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Majalah Farmasi dan Farmakologi
سال: 2020
ISSN: 2655-6715,1410-7031
DOI: 10.20956/mff.v24i2.10517